In the presented flip-flop, suppose the Enable signal is high, the S is low, and R is high. Now we set the Preset low (0) and the Clear high (1). In this condition, we expect Q=1 and Q'=0.
But checking the circuit gives us contradictory outputs. Because the Preset is low, the output of the upper NAND gate would be 1 and therefore Q=1. Since the R is high, the R* would be low (0) and therefore the output of the downside NAND gate would be also 1 or we can say Q^=1. That means both Q and Q' need to be high which is not possible.