Second Breakdown
(Many) Audio amplifiers operate the output stage in their linear region.
Modern power MOSFETs are not designed to operate in the linear region. Many of them (HEXFETS) are composed of a grid of hundreds of thousands of smaller FET elements to increase power density and switching speed. Other switching-optimized MOSFET families have similar constructions, with large die areas and/or arrays of smaller elements.
For MOSFETs, the threshold voltage has a negative temperature coefficient. As a particular area of the die / FET element gets hotter, it's threshold voltage decreases and since the MOSFET is operating in it's linear region, that area conducts a larger portion of the current, so it gets even hotter. Before long, the localized heating on a tiny fraction of the die has resulted in a short circuit, often called "Second Breakdown".
But...
A relatively new type of amplifier, the "Class D" amplifier, works by switching the output stage transistors on and off rapidly, at a frequency much higher than the speaker is expected to reproduce. A low-pass filter filters out the high-frequency noise, and amplification is achieved through varying the duty cycle.
MOSFETs are extremely common in such designs, as class D amplifiers either have the output stage elements fully on or fully off. As power MOSFETs are optimized for that, that's what they are used for.