I am designing a 4-layer PCB with 16 channels of LVDS (differential signalling, 480MHz). My layer stackup is Signal-GND-Power-Signal. A microstrip design for the LVDS channels is usually traces over a ground plane. However, I was wondering if it was possible to also have a controlled impedance differential pair on the OTHER signal layer, in which the adjacent copper plane is NOT ground, but in fact a power plane (in this case 3.3V).
If this is possible, would it be a good idea for some LVDS channels to run above this power plane, but then on the subsequent connector (That connects these LVDS channels to another board), that connector is referenced to ground (ground lines distributed throughout cable to minimize ground loops, instead of the power rail)?